Intellectual Property

Valtari Bio is the only company that has intellectual property specific to methods and approaches for diagnosing stroke, triaging stroke patients, and identifying time of stroke symptom onset. Please contact us to learn more about our IP portfolio.

Relevant Publications

Stroke-associated pattern of gene expression previously identified by machine-learning is diagnostically robust in an independent patient population. O’Connell GC, Chantler PD, Barr TL. bioRxiv. 2017 Mar 21.

Machine-learning approach identifies a pattern of gene expression in peripheral blood that can accurately detect ischemic stroke. O’Connell GC, Petrone AB, Treadway MB, Tennent CS, Lucke-Wold N, Chantler, PD, Barr TL. npj Genomic Medicine. November 2016.

The Role of Arginase 1 in Post-Stroke Immunosuppression and Ischemic Stroke Severity. Ashley B. Petrone, BS; Grant C. O’Connell, MS; Michael D. Regier, PhD; Paul D. Chantler PhD; James W. Simpkins, PhD; and Taura L. Barr, PhD RN. Translational Stroke Research. April 2016, Volume 7, Issue 2, pp 103-110.

A genomic profile of the immune response to stroke with implications for stroke recovery. Barr TL, VanGilder R, Rellick S, Brooks SD, Doll DN, Lucke-Wold AN, Chen D, Denvir J, Warach S, Singleton A, Matarin M, Biol Res Nurs. 2015 May;17(3):248-56. doi: 10.1177/1099800414546492. Epub 2014 Aug 14.

Admission neutrophil-lymphocyte ratio predicts 90-day outcome after endovascular stroke therapy. Brooks SD, Spears C, Cummings C, VanGilder RL, Stinehart KR, Gutmann L, Domico J, Culp S, Carpenter J, Rai A, Barr TL. J Neurointerv Surg. 2014 Oct;6(8):578-83. doi: 10.1136/ neurintsurg-2013-010780. Epub 2013 Oct 11.

Genomic biomarkers and cellular pathways of ischemic stroke by RNA gene expression profiling. Barr TL, Conley Y, Ding J, Dillman A, Warach S, Singleton A, Matarin M. Neurology. 2010 Sep 14;75(11):1009-14. doi: 10.1212/WNL.0b013e3181f2b37f.